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Skin & Recovery
GHK-CU 100mg
✓ 99.5% Purity (HPLC)
Molecular Weight
403.9 g/mol
CAS Number
49557-75-7
Form
Lyophilized powder
Use
Research only
$90.00
We accept
- Ships within 1–2 business days, discreetly packaged
- Lyophilized for research flexibility
- Third-party HPLC & endotoxin tested per batch
About
What is GHK-CU 100mg?
GHK-Cu is a tripeptide (glycyl-histidyl-lysine) that forms a 1:1 complex with copper(II) at physiological pH. GHK-Cu was first identified in human plasma in 1973 by Dr. Loren Pickart and has since become one of the most extensively characterized matrix-remodeling peptides in dermatological and wound-biology research.
Mechanism of Action
GHK-Cu has been shown in published literature to modulate gene expression of over 4,000 human genes — primarily related to collagen and elastin synthesis, metallothionein-driven antioxidant response, and anti-inflammatory cytokine profiles. Its copper-binding properties enable redox-active signaling in extracellular matrix remodeling.
Discovery & Context
Its discovery emerged from research into why plasma from younger donors appeared to enhance liver tissue repair. Since then, GHK-Cu has been characterized in 100+ peer-reviewed studies covering skin, hair, and extracellular matrix biology.
Research use only. Language such as "may," "appears to," and "has been shown in published studies" is used throughout to reflect the pre-clinical nature of this literature. Not intended for human consumption, diagnosis, or treatment.
Background
Research Context
Published research literature covers the following areas:
- Collagen and elastin synthesis regulation
- Metallothionein-mediated antioxidant response
- Hair follicle and dermal papilla studies
- Wound repair and tissue remodeling
- Copper coordination chemistry in biology
LAR supplies this compound as a reference standard to qualified laboratories. No dosing schedules, administration methods, or human-use guidance is provided or implied.
Literature
Selected References
- Pickart L. (2008). The human tri-peptide GHK and tissue remodeling. Journal of Biomaterials Science, Polymer Edition, 19(8), 969–988. PubMed 18644225 ↗
- Pickart L., Vasquez-Soltero JM. & Margolina A. (2015). GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration. BioMed Research International, 2015, 648108. Full text (PMC) ↗
- Pickart L. & Margolina A. (2018). Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data. International Journal of Molecular Sciences, 19(7), 1987. Full text (PMC) ↗
Handling
Storage & Stability
Sealed vial: Stable at refrigerated temperatures (2–8 °C) for up to 24 months. Stable at room temperature (up to 25 °C) for 30 days during shipping.
After opening: Refrigerate at 2–8 °C and use within 30 days. Protect from light. Do not freeze after opening.
Visual check: Solution should remain clear. Discard if discoloration or precipitate appears.
Lab Work
Certificate of Analysis
Every batch is independently tested for purity, mass, and endotoxin load. Click any report to view the full analysis.
Often Studied With
Pairs Well With
Questions
Frequently Asked
Is this FDA approved?
No. Research peptides supplied by LAR are reference materials for laboratory investigation. They are not approved by the FDA or any national regulatory body for human use.
Does this vial require reconstitution?
Yes. Vials ship as lyophilized powder, giving your lab control over solvent selection and final concentration. Reconstitution should follow your laboratory's standard practice.
How is purity verified?
Each manufacturing batch is tested by an independent third-party laboratory using HPLC-UV analysis. The full report, including chromatogram and mass spectrometry, is available above.
How long does shipping take?
Orders ship within 1–2 business days via discreet packaging.
