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Skin & Recovery
PT-141 – "WEHO" 10mg
✓ 99.55% Purity (HPLC)
Molecular Weight
1085.23 g/mol
CAS Number
1607799-13-2
Form
Lyophilized powder
Use
Research only
$70.00
We accept
- Ships within 1–2 business days, discreetly packaged
- Lyophilized for research flexibility
- Third-party HPLC & endotoxin tested per batch
About
What is PT-141 – "WEHO" 10mg?
PT-141, also known as bremelanotide, is a synthetic cyclic heptapeptide derived from Melanotan II via metabolic processing. It shows higher selectivity for MC3R and MC4R melanocortin receptors and has been extensively studied in central nervous system signaling literature.
Mechanism of Action
Acts primarily on MC4R receptors in the hypothalamic paraventricular nucleus. Published research characterizes effects on central sexual arousal pathways independent of the vascular mechanism utilized by PDE5 inhibitors.
Discovery & Context
Approved by the FDA under the brand name Vyleesi for hypoactive sexual desire disorder in premenopausal women in 2019. Continues as a research reference in melanocortin-pathway studies.
Research use only. Language such as "may," "appears to," and "has been shown in published studies" is used throughout to reflect the pre-clinical nature of this literature. Not intended for human consumption, diagnosis, or treatment.
Background
Research Context
Published research literature covers the following areas:
- MC3R / MC4R selective binding
- Central sexual arousal signaling
- Hypothalamic paraventricular nucleus research
- Cyclic peptide metabolite studies
LAR supplies this compound as a reference standard to qualified laboratories. No dosing schedules, administration methods, or human-use guidance is provided or implied.
Literature
Selected References
- Kingsberg SA. et al. (2019). Bremelanotide for the treatment of hypoactive sexual desire disorder: two randomized phase 3 trials. Obstetrics & Gynecology, 134(5), 899–908. PubMed 31599840 ↗
- Molinoff PB. et al. (2003). PT-141: a melanocortin agonist for the treatment of sexual dysfunction. Annals of the New York Academy of Sciences, 994, 96–102. PubMed 12851302 ↗
Handling
Storage & Stability
Sealed vial: Stable at refrigerated temperatures (2–8 °C) for up to 24 months. Stable at room temperature (up to 25 °C) for 30 days during shipping.
After opening: Refrigerate at 2–8 °C and use within 30 days. Protect from light. Do not freeze after opening.
Visual check: Solution should remain clear. Discard if discoloration or precipitate appears.
Lab Work
Certificate of Analysis
Every batch is independently tested for purity, mass, and endotoxin load. Click any report to view the full analysis.
Often Studied With
Pairs Well With
Questions
Frequently Asked
Is this FDA approved?
No. Research peptides supplied by LAR are reference materials for laboratory investigation. They are not approved by the FDA or any national regulatory body for human use.
Does this vial require reconstitution?
Yes. Vials ship as lyophilized powder, giving your lab control over solvent selection and final concentration. Reconstitution should follow your laboratory's standard practice.
How is purity verified?
Each manufacturing batch is tested by an independent third-party laboratory using HPLC-UV analysis. The full report, including chromatogram and mass spectrometry, is available above.
How long does shipping take?
Orders ship within 1–2 business days via discreet packaging.
